Resveratrol (3,5,4′-trihydroxy-trans-stilbene) is a stilbenoid, a type of natural phenol, the CAS NO is 501-36-0 and a phytoalexin produced naturally by several plants – especially the roots of the Japanese Knotweed, from which it is extracted commercially – when under attack by pathogens such as bacteria or fungi.
The effects of resveratrol are currently a topic of numerous animal and human studies. Its effects on the lifespan of many model organisms remain controversial, with uncertain effects in fruit flies, nematode worms, and short-lived fish. In mouse and rat experiments, anticancer, anti-inflammatory, blood sugar-lowering and other beneficial cardiovascular effects of resveratrol have been reported. In this article, we will talk about the use of resveratrol on Life extension.
Recently, a research by TsinghuaUniversity, lung nilfisk combined, named “resveratrol phosphatide compound nanometer emulsion projects” obtained the authorization of the United States Patent and Trademark Office (Patent No. US008465757B2).
It is reported, the patent complex synthesis of resveratrol and phospholipid, forming a unique distribution, the distribution system to form an emulsion particle size of less than 200 nm through high-pressure homogenizer or micro jet homogenizer. The advantage of the nanoemulsion is miscible with water in any ratio, and has good stability and bioavailability. The technology has been used for its elegant bright Platinum Series anti-aging skin care products.
Resveratrol is a famous SIRT1 protein activator, it was found in grape wine on 1940 for the first time, it was also found to contain resveratrol, after a study confirmed it as the main components of red wine health effect. In medicine, health food field, resveratrol has been widely used in anticancer, prevention and treatment of cardiovascular disease and weight reduction. The United States of America “anti-aging” has columned it to 100 one of the most 100 effective anti-aging substances.
Resveratrol used in cosmetics, can regulate energy metabolism through the activation of SIRT1 protein, the level of oxygen free radical, improve the genome stability, prolong the cell and the organism’s own life, so as to achieve anti-aging effects; resveratrol can down-regulate the expression of MCR1, decreased KIT, TYR, SLC45A2, MREG gene expression in a variety of signaling pathways inhibition of tyrosinase activity, blocking the formation and transport of melanin, brighten complexion. The performance and application of the College of life science, its joint Tsinghua University resveratrol were studied, the breakthrough to the application of nanometer lipid transfer technology, solves the resveratrol in water and lipid solubility of low, not easy to add into the formula and the skin transmission poor shortcomings, improve the solubility of resveratrol, transdermal absorption utilization rate and biological properties.
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