Isovanillin is widely used in food

Isovanillin is a phenolic aldehyde, an organic compound and isomer of vanillin. It is a selective inhibitor of aldehyde oxidase. It is not a substrate of that enzyme, and is metabolized by aldehyde dehydrogenase into isovanillic acid.

 

Isovanillin has the following purposes:

1. Isovanillin used as food flavor, daily flavor, pharmaceutical intermediates.

2. Isovanillin(CAS NO: 621-59-0) is good spices to obtain powder incense, fragrant beans. It often used as Foundation incense. Isovanillin can be widely used in almost all the flavor, such as violet, orchid, sunflower, oriental flavor in. Energy and Heliotropine, isoeugenol benzyl ether, coumarin, musk combined doubles are fixative, and the mixture with modifiers can also be used to mask bad breath. In food, tobacco flavor applications are wide, but the amount is higher. In Isovanillin Bean type, cream, chocolate, toffee flavor must be used in all spices.

3. Isovanillin is allowed spices used in food by Chinese regulations, it can be used as a fixative agent, is the preparation of Isovanillin flavor of the main raw material. Isovanillin can also be used directly for biscuits, cakes, candy, beverages and other food flavoring. Dosage normal production needs, usually in chocolate 970mg/kg; gum 270mg/kg; cakes, biscuits 220mg/kg; candy 200mg/kg; condiments 150mg/kg ~ cold drinks 95mg/kg.

4. GB 2760 2011 provides for the use of food flavors. Widely used in the preparation of Isovanillin, chocolate, butter flavor, etc., the amount of up to 25% to 30%, or directly used for cookies, cakes, the amount of 0.1% to 0.4%, 0.3%, 0.01% cold drinks, candy, 0.2% to 0.8% , especially with dairy products.

5. Isovanillin is an important synthetic fragrances, widely used in daily chemical products, for food, tobacco and alcohol use suitably refined. In the food industry, using a large amount of Isovanillin for the preparation of chocolate, cream and other flavor; the amount of up to 25-30%, directly in cookies, cakes, the amount of 0.1-0.4%, 0.01-0.3% cold drinks, candy 0.2-0.8%, especially with dairy products. Isovanillin can be used for chemical analysis, testing protein azaindene, phloroglucinol and tannic acid. In the pharmaceutical industry, for the production of antihypertensive drugs methyldopa, catechol drugs dopa and white within the stop, the enemy net and other bacteria.

6. Isovanillin can be used as standard reagents organic analysis

Production methods: N, N-dimethyl aniline salt sprig into salt, sodium nitrite nitrification off the nitroso-N, N-dimethylaniline hydrochloride. It with guaiacol, formaldehyde condensation at 41-43 ℃, then extracted with benzene. The first distillation, recrystallization from benzene, then a second distillation recrystallized from water. 50 ℃ drying products. Sulfite pulp waste solution containing structural units hinokitiol birch lignin sulfonates, oxidation under alkaline conditions, and then hydrolyzed vanillin obtained. Raw material consumption (kg / t) Yu guaiacol (98%) 1460 sodium nitrite 640N, N-dimethylaniline (98%)Hydrochloric acid (30%) 6000 formaldehyde (99%).

 

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Basic information of Anthranilic acid

Anthranilic acid, also known as anthranilic acid, 2 – amino acid, the chemical formula is C7H7NO2. Anthranilic acid is an aromatic amino acid, it is a white crystalline powder at room temperature. Anthranilic acid is used for pharmaceuticals, dyes, fragrances and pesticide intermediates.

Anthranilic acid(CAS NO: 118-92-3) is a white to pale yellow, odorless crystalline powder with a sweet taste, soluble in water, ethanol and ether, slightly soluble in benzene, insoluble in cold water.  When Anthranilic acid plus sublimation, distillation decomposition of aniline and carbon dioxide. It may form chelates with metal ions. In the glycerol solution was zishi color fluorescence.

Anthranilic acid used as medicine, dyes, spices and pesticide intermediates. It can be used to produce dyes aspects anthraquinone dyes, azo dyes and indigo dye family, such as neutral blue BNL, Disperse Yellow 5G, Disperse Orange GG, Disperse Yellow GC, Reactive Brown K-B3Y. in Medicine, Anthranilic acid can be used to produce mefenamic acid, often phenanthroline, inflammatory pain Jing, Forensic and so on.

Anthranilic acid may also be used in organic synthesis for the Production of 3 – hydroxy-indole and methyl anthranilate and other compounds. It also used as a chemical reagent, a determination of silver, magnesium, mercury, cadmium, nickel, zinc, cobalt, lead, cerium, copper, manganese, palladium and uranium and other metal complexing reagents.

Because anthranilic acid and acetic anhydride and o-toluene when the cyclization reaction with addictive non-barbiturate hypnotics methaqualone, anthranilic acid can also be used to synthesize new methaqualone, Therefore, anthranilic acid and its derivatives use is restricted in some countries. In the United States, the U.S. Drug Enforcement Administration considers Anthranilic acid and its salts and esters as the first class of controlled precursor chemicals. September 2006 China Ministry of Commerce, Ministry of Public Security announced the “precursor chemicals import and export regulations of international verification” accessories: international verification of precursor chemicals management directory, the above synthesis intermediates Acetylsalicylic acid as the first precursor chemicals, anthranilic acid itself are classified as second class of precursor chemicals.

Diazotized anthranilic acid occurs resulting diazonium salt is in the heating elimination of nitrogen and carbon dioxide, a highly active 1,2 – phenyl acetylene. Generated benzyne dimerization can occur immediately dibenzo cyclobutane.

 

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A Cyclopropyl methyl ketone project

Production name: Cyclopropyl methyl ketone

English Synonyms: Acetylcyclopropane; ACETYLTRIMETHYLENE; AKOS BBS-00004282; 1-CYCLOPROPYL-1-ETHANONE; 1-CYCLOPROPYL-ETHANONE; CPMK; METHYL CYCLOPROPYL METHYL KETONE; 1-cyclopropyl-ethanon; Cyclopropylethanone; Ketone, cyclopropyl methyl; ketone, cyclopropylmethyl

CAS No: 765 -43-5

EINECS No: 212 -146-4

Molecular formula: C5H8O

Weight: 84.12

InChI:  InChI = 1/C5H8O/c1-4 (6) 5-2-3-5/h5, 2-3H2, 1H3

Density: 0.903

Boiling point: 114 ℃

Flash point: 21 ℃

Characters: Appearance colorless or very pale yellow transparent liquid

Usage: Used as pharmaceutical and pesticide intermediates

Category: Organic Chemicals / carboxylic acid / carboxylate

 

Project Name: Cyclopropyl methyl ketone production process

Cyclopropyl methyl ketone as an emerging pharmaceutical intermediate is the anti-AIDS drugs by fluorine polyvinyl alcohol (Efavirenz, Sustiva, Stocrin) and Il Lei Min (Yierleimin) key intermediate, according to DuPont fluorine PVA is developed anti-AIDS drugs, the synthesis is required before this material.

Cyclopropyl methyl ketone is also an important pesticide intermediate, it can be used for synthetic pesticides Cyprodinil, as well as synthetic broad-spectrum antibacterial agent ciprofloxacin new drugs and pyrethroid pesticides is an important intermediate, after reduction of chiral chiral alcohol after has become an important drug. In the spice ketone, methyl ketone either itself as a spice or as synthetic intermediates of spices, has played an important role, is widely used in the synthesis of pharmaceuticals and pesticides.

Economic Indicators: The project raw material costs of approximately about 110 yuan per kilogram.

Project purposes: organic synthesis and drug synthesis intermediates.

The maturity of the project: The project technology is quite mature; the production processes a small amount of acidic wastewater discharge. Industrialization needs no special equipment, just conventional chemical production equipment, the general chemical companies can successfully put into this project. After the transfer, it can provide all the technical information produced by the project and on-site technical guidance.

 

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The side effects of Vinblastine sulfate

Vinblastine sulfate has the formula: C46H58N4O9 • H2SO4. Its molecular weight is: 909.06. Vinblastine sulfate is a white or almost white loose-shaped or amorphous solid. Vinblastine sulfate has a hygroscopic, in the case of light or heat easy to turn yellow.

Vinblastine sulfate (CAS NO: 143-67-9) is an antineoplastic agents, it can be used to treat Hodgkin’s disease and choriocarcinoma. Vinblastine sulfate also have a certain effect on lymphosarcoma, acute leukemia, breast cancer and other tumors.

Vinblastine sulfate as an effective anti-cancer drug, which is widely used in the pharmaceutical industry, but Vinblastine sulfate also has a lot o side effects. In this article, I will stand on the patient’s point of view and talk about the side effects of Vinblastine sulfate.

Firstly, after injecting Vinblastine sulfate, pain or redness may at the injection site, nausea, vomiting, constipation, tiredness, and loss of appetite may occur. Nausea and vomiting can be severe. In some cases, your doctor may prescribe medication to prevent or relieve nausea and vomiting. Eating several small meals, not eating before treatment, or limiting activity may help lessen some of these effects. If these effects persist or worsen, tell your doctor or pharmacist promptly.

Using Vinblastine sulfate may cause constipation. To reduce constipation, you should increase your intake of fiber, drink plenty of water, and exercise. Stool softeners may be helpful. Ask your doctor or pharmacist about stool softeners and laxatives.

Temporary hair loss is another common side effect, when you using Vinblastine sulfate, so normal hair growth should return after treatment has ended.

Many people using Vinblastine sulfate may have serious side effects. However, your doctor has prescribed Vinblastine sulfate because he or she has judged that the benefit to you is greater than the risk of side effects. Careful monitoring by your doctor may decrease your risk.

Painful sores on the lips, mouth, and throat may occur, if you are taking Vinblastine sulfate. To decrease the risk, you need to limit hot foods and drinks, brush your teeth carefully, avoid using mouthwash that contains alcohol, and rinse your mouth frequently with cool water.

Tell your doctor right away if you have any serious side effects after using Vinblastine sulfate, including: easy bleeding/bruising, fast/pounding heartbeat, abdominal/stomach pain, bone/jaw pain, severe headache, hearing problems, unusual lumps/skin changes, dizziness/feeling of spinning, mental/mood changes (e.g., depression), pale/bluish fingers/toes, pain/coldness in fingers/toes, numbness/tingling, difficult/painful urination, pink/bloody urine.

Get medical help right away if any of these rare but very serious side effects occur: sudden shortness of breath/wheezing, black/tarry stools, chest/left arm pain, confusion, seizures, slurred speech, weakness on one side of the body, vision changes, vomit that looks like coffee grounds.

Vinblastine sulfate can lower the body’s ability to fight an infection. Tell your doctor promptly if you develop any signs of an infection such as fever, chills, or persistent sore throat.

A very serious allergic reaction to Vinblastine sulfate is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. And if you want to learn more information about Vinblastine sulfate, you can access to guidechem.com.

 

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Prolonged decline in the price of lithium cobalt oxide lead based lithium carbonate price pressure

It was observed that lithium cobalt prices were long-term downtrend, based lithium carbonate price pressure. From the global lithium battery cathode materials development, China’s current level of technology is not very advanced technology in many areas there is still a bottleneck.

Lithium cobalt oxide is made by the lithium carbonate (CAS NO: 554-13-2) oxide according to cobalt / lithium (atomic ratio) = 1 ratio. Ternary materials as nickel, cobalt, manganese, according to a certain proportion, then import prepared from lithium source. The lithium manganate and lithium hydroxide or lithium manganese oxide or manganese salt is made.

Based on different routings, production of lithium iron phosphate cathode material technology roadmaps are mainly traditional high-temperature solid-phase method and carbothermal reduction method. The traditional high-temperature solid-phase method use lithium carbonate, ammonium dihydrogen phosphate, ferrous oxalate synthesis and other materials to make lithium iron phosphate, the represent companies are the United States on behalf of enterprise A123, Tianjin Stellan and Pulead. Carbothermal reduction use red iron oxide, synthetic lithium dihydrogen phosphate and any other materials to make lithium iron phosphate, the represent companies are the United States Valence and BTR.

Due to technical problems, domestic lithium dihydrogen phosphate, phosphate and lithium ratio is difficult to do accurately, resulting in inconsistent quality materials, which ultimately affects the lithium iron phosphate product quality stability. The high-quality lithium dihydrogen phosphate to be imported, the price is higher. To circumvent the use of lithium dihydrogen phosphate, some companies using the traditional high-temperature solid-phase method, this method under the three kinds of raw materials preparation technology is very mature, and supply security. Canada Phostech companies and other enterprises of Zhejiang Zhenhua iron phosphate and lithium carbonate synthesis using lithium iron phosphate technology, this process makes fewer types of raw materials, the subsequent process control more streamlined, but requires a higher quality iron phosphate.

At present, lithium cobalt oxide cathode material is still mainly ternary material, lithium manganese oxide and lithium iron phosphate sales growth rates are lower than the global level. 2011 and 2012 domestic cathode material production growth was 24%, 39%, while output growth of only 9%, 13%, mainly due to lithium cobalt prices continued to fall. Subject to the pressure of the cost of production of electric vehicles, lithium long term downward trend in prices, since lithium battery manufacturers production cost control, lithium battery cathode material (mainly lithium cobalt oxide) prices are also declining, domestic positive materials production enterprises lower margins, so that the upstream lithium carbonate prices under pressure.

 

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The role of Oxalic acid dehydrate

As a bleaching agent

Oxalic acid dihydrate is mainly used as a reducing agent and bleach, Oxalic acid dehydrate used for the production of drugs such as antibiotics and borneol and refining rare metals solvents, dye reducing agent, tanning agent. Oxalic acid can also be used cobalt – molybdenum – alumina catalyst production, metal and marble cleaning and bleaching of textiles. For metal surface cleaning and processing, rare earth extraction, textile, leather processing, catalyst preparation and so on.

 

As a reductant

In organic synthesis industry, Oxalic acid dehydrate(CAS NO: 6153-56-6) is mainly used for the production of hydroquinone, pentaerythritol, cobalt oxalate, nickel oxalate, gallic acid and other chemical products. In Plastics industry, Oxalic acid dihydrate used for the production of polyvinyl chloride, amino plastics, urea-formaldehyde plastics, paint chips and so on.

 

Oxalic acid dihydrate dye industry for the manufacture of base light green and so on. In Printing and dyeing industry Oxalic acid dihydrate can replace acetic acid, used as a pigment dye color help agent, bleaching agent. In pharmaceutical industry Oxalic acid dehydrate is used for the manufacture of chlortetracycline, oxytetracycline, tetracycline, streptomycin, ephedrine.

 

In addition, Oxalic acid dihydrate can be used for the synthesis of various oxalate, oxalate and oxamide and other products, and to diethyl oxalate and sodium oxalate, calcium oxalate, etc. largest output.

 

As a mordant

Oxalic acid dihydrate can be used for antimony mordant, ferric ammonium oxalate is printed blueprint agents.

 

Descaling function

Oxalic acid dihydrate is used to rust. It generates acid oxalate when rusted.  Acid oxalate has Great solubility. But Oxalic acid dihydrate has some toxicity, when used it, do not use containers holding food on the line. However, be careful when using oxalic acid has a strong corrosive to stainless steel. High concentration of oxalic acid is also susceptible to corrosion hands.

 

Oxalic acid can rust, to sell the store to buy a bottle of chemical reagents oxalic acid, take some warm water solution dubbed rub on the rust stains. Shop selling oxalic acid, generally also sell some medical equipment, glassware oxalic acid can rust, but there are certain toxic soluble in water and alcohol, when used, do not eat or drink on the line, then rub with emery paper, and finally spray paint.

 

 

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Hydroquinone may damage you Chromosomal and DNA

Many results show that hydroquinone has a wide range of genotoxicity, it can lead to chromosomal aberrations, sister chromatid exchange (SCE), DNA-protein cross-links, DPC, DNA-DNA cross-linking, DNA strand breakage and so on.

 

Chromosomal Damage

 

Syrian hamster V79 cells in vitro toxicological test results show that hydroquinone (CAS NO: 123-31-9) can cause cell mutations, chromosomal aberrations, sister chromatid exchange and induce cell transformation.

 

It was reported, hydroquinone treatment can occur chromosomal aneuploidy, polyploidy, chromosomal deletions, sister chromatid exchange and other effects. Zhang L, etc. found that the use of fluorescence in situ hybridization, hydroquinone induced human lymphocytes 5 and 7 chromosome4q, causing HL60 cells on the 7th and the 9th chromosome aneuploidy effect.

 

Eastmond and other human lymphocytes treated with hydroquinone also appeared similar phenomenon, and found in the bone marrow pluripotent hematopoietic stem cells, CD34 + cells compared with CD34-cells are more sensitive to hydroquinone, and in human CD34 + CD19-cells in the bone marrow , hydroquinone induced selective deletion of chromosome 7 and 5q31, no effect on chromosome 8. Because of persistent structural chromosome abnormalities and number of leukemia cases in humans are often observed, therefore, hydroquinone chromosome damaging effects of its cause bone marrow or blood abnormalities of internal factors.

 

DNA Damage

 

Hydroquinone can be damaged by a variety of ways DNA. It has been reported, under neutral conditions hydroquinone spontaneously oxidized to produce superoxide anion, and a quinone compound semiquinone.

 

Superoxide anion can lead to hydrogen peroxide (H2O2) and hydroxyl radicals (• OH) radical chain reaction, and into the cells, the DNA formed near • OH; superoxide anion can be protonated, across the membrane and DNA near • OH produced H2O2, produce oxidative damage to DNA.

 

Ceusilva such as hydroquinone exposure with V79 cells, oxidative DNA damage was detected reflect the characteristic Indicator 8 – hydroxy – base guanine (8-OH-G) content. The results show that they have significantly increased trend. 8-OH-G can cause mutations that induce DNA strand breaks, and has been reported with its content micronucleus formation has some relevance. Another mechanism of DNA damage may be due to the oxidation of hydroquinone product inhibition of DNA topoisomerase II activity, Leu et al found that the oxidation products of hydroquinone, 1,4 – benzoquinone and 4,4 ‘- benzoquinone can inhibit the DNA chain on protein–topoisomerase II.  DNA-topoisomerase II is an SH group-dependent endonucleases, DNA topoisomerase II by cleavage of the purine / pyrimidine repeat sequences involved in DNA replication, recombination, and structural maintenance of chromosome segregation. Once topoisomerase II is destroyed, will lead to DNA helicase, releasing DNA circles (100p), causes DNA strand breaks, DNA strand breaks may induce DNA strand inappropriate regrouping exception occurred mitotic recombination, abnormal restructuring will lead to cell death or chromosomal mutations.

 

DNA damage and genetic structure of the abnormal and the resulting expression of oncogenes and tumor suppressor genes or functional changes in cell mutations and malignant transformation is a prerequisite.

 

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Telling you something about Ammonium bifluoride

Formula of Ammonium bifluoride:  NH4HF2

 

Molecular weight of Ammonium bifluoride:  57.04

 

Properties of Ammonium bifluoride:

Ammonium bifluoride (CAS NO: 1341-49-7) is a kind of White or colorless orthorhombic crystals. The commodity of Ammonium bifluoride is often flaky, may slightly sour. The relative density is 1.52. Melting point is 125.6 ℃. Boiling point is 240 ℃. It is easy to deliquescent in the air, slightly soluble in alcohol, easily soluble in cold water, hot water decomposition. The aqueous solution of Ammonium bifluoride is strongly acidic. Ammonium bifluoride can be sublimated at higher temperatures. It can corrode glass, corrosive to the skin. Ammonium bifluoride is a kind of toxic chemical.

 

Uses of Ammonium bifluoride:

Ammonium bifluoride is not only used for glass etching agents, disinfectants, preservatives, solvents beryllium, silicon steel plates of the surface treatment agent, but also used for the manufacture of ceramic and magnesium alloys.

 

Be careful of Ammonium bifluoride:

This product is toxic. The operator must wear protective equipment. If they touch the skin, immediately flush with water and then immersed in 70% ice to the affected area cold ethanol or magnesium sulfate solution 30min, then cover with magnesium glycerol ointment. Pay particular attention to the skin under the nail, if not timely cleaning process, will lead to severe pain.

 

Packaging and storage:

Packaging Ammonium bifluoride with woven bag lined with polyethylene plastic. The Net weight of the package may be 25kg or 50kg. The packaging should be obvious “drugs” signs. It belongs to inorganic drugs, the IMDG Code is 83019. Ammonium bifluoride should be stored in a cool, dry, clean warehouse, the maximum temperature does not exceed 25 ℃. During transport to prevent rain, sun exposure is strictly prohibited. Loading and unloading should gently packaging to prevent breakage. .

 

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What is Hydrofluoric Acid

Name of this production:  Hydrofluoric Acid  

 

Physical and chemical properties of Hydrofluoric Acid

Hydrofluoric acid is an aqueous solution of hydrogen fluoride gas, is a colorless to pale yellow transparent liquid smoke. It has a pungent odor. MF is HF-H2O. CAS NO is 7664-39-3. The relative density of 1.15 to 1.18. Boiling point 112.2 ℃ (percentage by weight of 38.2%). Usually commercially available concentration: approximately 47%. It is a kind of weak acid.

 

Pathways of Hydrofluoric Acid

Hydrofluoric Acid can be absorbed through the skin, by inhalation of hydrofluoric acid mist.

 

Toxicological Profile of Hydrofluoric Acid

There is a strong skin irritant and corrosive. Hydrofluoric acid, hydrogen ions in the human tissue dehydration and corrosion, and Fluorine is one of the most active non-metallic elements. Skin contact with hydrofluoric acid, fluoride ion dissociation continued to infiltrate deep tissue, dissolve the cell membrane, resulting in the epidermis, dermis, subcutaneous tissue, muscle and even liquefaction necrosis. Fluoride can also interfere with the activity of enolase skin cells oxygen uptake was inhibited. Estimated human intake of 1.5g hydrofluoric acid can cause immediate death.

 

Inhalation of high concentrations of hydrofluoric acid mist may cause bronchitis and hemorrhagic pulmonary edema. Hydrofluoric acid can also be absorbed through the skin and cause severe poisoning.

 

Clinical of Hydrofluoric Acid

Skin damage relates to hydrofluoric acid concentration, contact time, contact area and the processing methods. The higher the concentration, the longer the contact time, suffer more soft or dense tissue, the more rapid and intense action. Contact with hydrofluoric acid concentration of at least 30%, pain and lesions often occur immediately. Exposure to low concentrations, pain and skin burns are often beginning after a few hours.

Early lesions were localized erythema, flush immediately turned white edema, necrosis, and then into the gray light cyan, and then re-order tan or black thick scab, scab off after the formation of ulcers. Finger parts damage often turned bullae, deck often simultaneously involved, the nail bed and periungual swelling.

A blister formation under severe may lead the nail bed and deck separation. Burns often has high concentrations of necrosis, ulcer healing slowly. In severe cases involving the partial skeleton, particularly the phalanx is more common. Interphalangeal joints showed narrow articular surface roughness, the edge is not sharp, cortical hyperplasia, narrow canal, and even bone resorption and similar signs of osteomyelitis. Hydrofluoric acid mist can cause skin itching and dermatitis. In large doses can cause skin, gastrointestinal tract and respiratory tract burns. Eye exposure to high concentrations of hydrofluoric acid, local pain, and the rapid formation of a white pseudomembranous opacities, such treatment is not timely can cause corneal perforation. Hydrofluoric acid burns merger fluorosis has attracted attention, patients with hypocalcemia convulsions, QT interval prolongation, ventricular fibrillation episodes.

 

Handle of Hydrofluoric Acid touch

After contact with skin immediately with plenty of water for a long time thoroughly rinsed and washed as soon as possible to dilute hydrofluoric acid. This is the most effective measure, the key to treatment. Hydrofluoric acid burns a lot after neutralization method, the general principle is to use some soluble calcium, magnesium salts preparations, combine it with fluoride ions to form insoluble calcium fluoride or magnesium fluoride, so fluoride ion inactivated.

Lime or soaking wet field applications are easy to spread. Ammonia and hydrofluoric acid to form a corrosive amine fluoride, it is not appropriate as a neutralizer. Hydrofluoric acid burns treatment solution (5% calcium chloride 20ml, 2% lidocaine 20ml, dexamethasone 5mg) or soaking wet.

Using the magnesium sulfate saturated liquid as an ice immersion. DC calcium penetration. The use of the role of DC, so that a sufficient amount of calcium ions directly into the site in need of treatment to improve the topical effect. In burns 1 to 3 days, 1 to 2 times a day, every 20 to 30 minutes.

Severe cases the discretion to extend the time for each treatment. Hydrofluoric acid splashed into eyes, immediately separated the eyelids, continuous flushing with plenty of water for about 15 minutes. Drop 2 to 3 drops of local anesthetic eyedrops, to relieve pain and sending ophthalmic treatment as soon as possible.

 

 

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Can acycloguanosine do long-term use?

After absorption of acycloguanosine tablets into herpes virus infected cells, and competition virus thymidine nucleoside kinase or cellular kinases, the drug is activated phosphorylated acycloguanosine triphosphate, which interferes with viral inhibition of viral DNA polymerase replication of herpes simplex virus, varicella zoster virus, cytomegalovirus, etc. with inhibition. So, long-term acycloguanosine (CAS NO: 59277-89-3) tablets eat it? Long to eat will be resistant to it?

 

Resistance (Resistance to Drug), also known as drug resistance, is the parasites, microorganisms and tumor cells to chemotherapeutic drug tolerance, drug resistance, once produced, role of chemotherapy drugs decreased. When the long-term use of antibiotics, the majorities continue to be killing sensitive strains, resistant strains to multiply, instead of sensitive strains, leaving the kind of bacterial drug resistance rate continues to rise. The latter approach is currently considered the main reason for generating resistant.

 

Resistance can be divided according to their causes acquired drug resistance and natural resistance. The nature of the pathogens, such as bacteria can also be present a certain a natural resistance. In order to maintain the effectiveness of antibiotics, you should pay attention to their rational use. Well, you know the long-term use of acycloguanosine tablets do? Long-term drug use can do?

 

Acycloguanosine tablets should be based on how fast your condition to follow the doctor’s guidance, you do not have to listen to the doctor with a long-term proposal, as will the resistance, for now, still no certain information or documents display.

 

Guidchem.com Reminder you: medication to regulate, follow the doctor’s advice and guidance, do not mess with drugs. Guidchem.com sales acycloguanosine tablets, the price concessions, in line with national pharmaceutical standards.

 

 

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